While baseball cards have been around since the late 1800s, it was Topps who popularized modern trading cards with their iconic designs released in the 1950s. Since then, Topps has produced billions of baseball cards, with some becoming hugely valuable today. Whether it’s rare errors, iconic rookies, or historic moments captured, certain Topps cards can fetch thousands—even hundreds of thousands—at auction.

One of the most expensive and sought-after baseball cards ever is the iconic 1952 Topps Mickey Mantle in near-mint condition. Considered the “Mona Lisa” of sports cards, a PSA 9 graded Mantle sold for $5.2 million in 2021, setting records. What makes it so valuable? It was Mantle’s rookie card released during his Triple Crown season when he was already a rising star at age 20. Very few high-grade examples survive today in the pristine condition collectors desire.

Another hugely valuable Topps rookie is the 1909-11 T206 Honus Wagner. Though it was part of the iconic T206 series rather than a true “rookie” since Wagner was already a star, its rarity and subject still make it the holy grail for collectors—one in a PSA 8 condition was sold for $6.6 million in 2016. It’s believed Wagner demanded his image be removed from production, leaving only 50-200 known to exist today in any condition.

For a true post-WWII rookie card, the 1952 Topps Willie Mays is also extremely valuable. As one of the game’s all-time greats and also capturing his rookie season playing for the New York Giants, high-grade Mays rookies can sell for over $500,000. Like Mantle, very few survived the years in pristine condition.

Rookie cards aren’t the only ones that can be worth a fortune. Historic or extremely rare variations can also make certain Topps cards enormously valuable. A 1967 Topps Nolan Ryan rookie card with an error featuring him in a Los Angeles Dodgers uniform rather than his actual Angels uniform sold for $240,000 in 2018 since it’s a true anomaly.

The iconic 1968 Topps Roberto Clemente is another highly valued card for capturing a HOFer and his career .317 batting average, as well as being released shortly before his tragic death in a plane crash at age 38. A PSA 9 recently sold at auction for over $90,000.

Perhaps the rarest Topps variation ever found is the 1952 Mickey Mantle commons reverse negative. Instead of the photo being printed correctly, this one card had Mantle’s image reversed by mistake. After being lost in a collector’s attic for decades, it resurfaced and sold in 2021 for $312,000, setting a record for the highest price paid for a single modern card.

While those examples show the extreme high-end, there are also many valuable Topps cards worth collecting that can be had for thousands. The 1954 Topps Hank Aaron rookie in good condition is valued around $4,000 raw or $15,000 graded PSA 8. The 1956 Topps Sandy Koufax rookie in similar grade is worth $6,000-$10,000.

The 1964 Topps Sandy Koufax that captures his perfect game is also valued around $4,000 raw or $10,000 PSA 8 since it commemorates such a historic achievement. And the 1969 Topps Tom Seaver rookie, showing the HOFer during his Rookie of the Year season with the Mets, can reach $3,000 ungraded or $12,000 PSA 9.

For investors, the 1970 Topps Nolan Ryan rookie remains a steady riser since he’s one of the most dominant pitchers ever. Ungraded examples are around $2,000 now but a PSA 9 brings over $15,000. And the 1975 Topps Fred Lynn rookie, which honors the AL MVP and Rookie of the Year, rises steadily and can reach $2,000 raw or $8,000 PSA 9.

While modern issues after the 1980s don’t carry the same cachet as vintage, certain stars’ rookie cards retain value. Raw copies of the 1987 Topps Chipper Jones rookie are around $150 but a PSA 10 gem is worth $1,000. And the 1992 Topps Derek Jeter rookie remains popular—a PSA 9 brings over $500 today.

While it takes serious money to acquire the true crown jewels like the Mantle and Wagner rookie cards, savvy collectors can still profit by finding affordable gems from the 1950s and 60s produced by Topps. Whether it’s a star’s first card, rare errors, or historically significant designs, certain issues will always retain demand. With patience and knowledge of what to look for, valuable Topps cards are out there waiting to be unearthed.