The baseball cards produced in the early 2000s featured many star players who were just starting their careers in Major League Baseball. While it takes years for rookie cards to gain significant value, some from this era have already become quite valuable due to the success and popularity of these players. Here are some of the most valuable baseball rookie cards from the 2000s.

Derek Jeter 1996 Topps #291

Widely considered one of the greatest shortstops of all time, Derek Jeter established himself as a superstar in his rookie season of 1996 with the New York Yankees. His 1996 Topps rookie card #291 has become extremely valuable over the years. Graded PSA 10 Gem Mint copies of this card innear-perfect condition have sold for over $400,000, making it one of the highest valued cards from the 1990s and 2000s. Even well-centered PSA 9 Excellent copies can fetch $10,000-$20,000. This is undoubtedly Jeter’s most desirable rookie card due to its iconic design from his first Topps issue.

Chipper Jones 1991 Fleer #91

A Hall of Fame bound player, Chipper Jones had a legendary 19-year career entirely with the Atlanta Braves. His true rookie card came in 1991 Fleer and has steadily gained value over time. High-grade PSA 10 versions have reached $80,000-$100,000 at auction recently. Even PSA 9s in the $15,000 range show how coveted this card has become for Jones collectors. While not his first card issued, the 1991 Fleer is generally agreed to be Chipper’s true rookie as it was his inaugural season in the major leagues.

Mariano Rivera 1991 Classic Best #232

As arguably the greatest closer of all-time, Mariano Rivera dominated for 19 seasons out of the New York Yankees bullpen. His 1991 Donruss Classic Best rookie card #232 has emerged as one of the more valuable cards from the early 1990s. PSA 10 Gem Mint examples have sold for $60,000, demonstrating strong interest from Yankees collectors. Even well-centered PSA 9 copies can sell for $10,000. Rivera’s Hall of Fame career and iconic status as “Mo” the Yankees closer has made this one of his most collectible rookie issues.

Ken Griffey Jr. 1989 Upper Deck #1

Many consider Ken Griffey Jr. to be the best all-around player of the 1990s. His rookie card, the coveted 1989 Upper Deck #1, has achieved legendary status and value over the past 30+ years. PSA 10 versions regularly sell for $100,000 or more, with some graded Gem Mint copies setting auction records above $250,000. Even PSA 9s in the low five-figure range show how sought after this card remains. It’s often argued this is the most desirable rookie card in the modern era due to Griffey’s phenom talent and popularity combined with the historic introduction of Upper Deck brand in 1989.

Alex Rodriguez 1987 Topps Traded #73T

Although he made his MLB debut with the Seattle Mariners in 1994, Alex Rodriguez’ true rookie card came in 1987 Topps Traded from his time in the minors with the Texas Rangers organization. Graded PSA 10 copies of the #73T have sold for $80,000 while PSA 9s bring $15,000-$20,000. Rodriguez cemented his Hall of Fame credentials despite PED controversies, and the scarcity of his early traded card makes it a must-have for collectors of A-Rod and the late 1980s/early 1990s era. It remains one of the most valuable MLB rookies from that time period and before his widespread stardom with Seattle and New York Yankees.

Albert Pujols 2000 Bowman Chrome #BC-4

One of the best pure hitters of all time, Albert Pujols dazzled from the very beginning of his career with the St. Louis Cardinals. His first widely available rookie card came in the 2000 Bowman Chrome set, with the ultra-short printed refractors being exceptionally rare and valuable. High-grade PSA 10 versions have reached six figures, with especially scarce printing plate copies achieving record prices above $250,000. Even well-centered PSA 9s comfortably sell in the $5,000+ range. Pujols went on to have a legendary 21-year career that has made this one of the most iconic and investment-worthy rookies from the 2000s era.

David Ortiz 1996 SP Authentic #75

While Big Papi made his MLB debut in 1997, many consider his true rookie card to be the 1996 SP Authentic #75 from when he was a touted prospect in the Twins farm system. High-grade specimens in PSA 10 have reached $60,000 at auction. In PSA 9 condition, examples still fetch over $10,000 showing the strong demand. Ortiz would go on to cement his Hall of Fame legacy across 14 seasons with the Boston Red Sox where he was a clutch postseason hitter and helped the club win 3 World Series. This elusive early card captures Ortiz on the cusp of his legendary career.

Ryan Howard 2001 Bowman #96

In his debut 2005 season, Ryan Howard established himself as one of baseball’s premier power hitters by slamming 58 homers and winning the National League Rookie of the Year Award for the Philadelphia Phillies. For collectors, his first mass-produced card came in 2001 Bowman as the #96 prospect. PSA 10 Gems have reached $20,000 with most PSA 9s selling around $6,000. Howard’s monstrous early Phillies career has kept this among the most collectible MLB rookies from the early 2000s set.

While it takes many years for rookies to accrue significant value, the success and popularity of these particular players from the 2000s era have already made their early cards quite collectible and expensive. As their careers evolve into Hall of Fame consideration and their accomplishments become more ingrained in baseball history, expect prices to potentially climb even higher still for these iconic rookie cards.